Type 1 diabetes mellitus: pathogenesis, symptoms and therapy
نویسندگان
چکیده
منابع مشابه
On type 1 diabetes mellitus pathogenesis
Type 1 diabetes mellitus (T1DM) results from the autoimmune destruction of β cells of the endocrine pancreas. Pathogenesis of T1DM is different from that of type 2 diabetes mellitus, where both insulin resistance and reduced secretion of insulin by the β cells play a synergistic role. We will present genetic, environmental and immunologic factors that destroy β cells of the endocrine pancreas a...
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Objective(s): Diabetes mellitus (DM) is a major worldwide public health challenge, for which gene therapy offers a potential therapeutic approach. To date, no systematic review or meta-analysis has been published in this area, so we examined all relevant published studies on rodents to elucidate the overall effects of gene therapy on bodyweight, intraperitoneal glucose...
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ژورنال
عنوان ژورنال: Orvosi Hetilap
سال: 2010
ISSN: 0030-6002,1788-6120
DOI: 10.1556/oh.2010.28836